发明名称 |
NOVEL AMIDE DERIVATIVE AND USE THEREOF AS MEDICINE |
摘要 |
Provided are a novel low-molecular-weight compound that suppresses production of induction type MMPs, particularly MMP-9, rather than production of hemostatic type MMP-2, as well as a prophylactic/therapeutic drug for autoimmune diseases or osteoarthritis. An amide derivative represented by the following formula (I) wherein each symbol is as defined in the specification, or a pharmacologically acceptable salt thereof. |
申请公布号 |
US2013040930(A1) |
申请公布日期 |
2013.02.14 |
申请号 |
US201113643790 |
申请日期 |
2011.04.27 |
申请人 |
MITSUBISHI TANABE PHARMA CORPORATION;MAEDA KAZUHIRO;ENDOH JUN-ICHI;TARAO AKIKO;TASHIRO KAORU;ISHIBUCHI SEIGO;HIKAWA HIDEMASA |
发明人 |
MAEDA KAZUHIRO;ENDOH JUN-ICHI;TARAO AKIKO;TASHIRO KAORU;ISHIBUCHI SEIGO;HIKAWA HIDEMASA |
分类号 |
A61K31/496;A61K31/454;A61K31/4545;A61K31/506;A61K31/5355;A61K31/5377;A61K31/549;A61K31/55;A61K31/551;A61P1/00;A61P19/02;A61P25/00;A61P29/00;A61P37/06;C07D401/14;C07D403/10;C07D413/14;C07D417/10;C07D417/14;C07D471/04 |
主分类号 |
A61K31/496 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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