| 摘要 |
The present invention relates to a method for manufacturing metal nanoparticles having surface-enhanced Raman scattering (SERS) activity, which is characterized in that the method comprises a step of mixing an aqueous metal salt solution, an aqueous cyclodextrin solution, and an aqueous sodium hydroxide solution. In the method for manufacturing the metal nanoparticles according to the present invention, metal salts are reduced through a one-pot process using cyclodextrin in an aqueous solution at room temperature, thereby simplifying the process and achieving superior processing efficiency. In addition, since the cyclodextrin functions as a reducing agent and as a protecting agent in the aqueous solution, making a separate organic reducing agent unnecessary, the manufacturing process is environmentally-friendly. The metal nanoparticles can be obtained in various shapes and sizes, such as a sphere, a polygon, a nanorod, a nanowire, a nanoflower, etc., simply by controlling the concentrations of reactants and the reaction temperature. Further, the thus-obtained various kinds of metal nanoparticles have superior SERS activity and can therefore be applied in a biosensor for detecting biomaterials in the field of biomedicine. |
