发明名称 APPLICATION OF ACTIN-BINDING PROTEIN TO DISEASE ASSOCIATED WITH CELL MOTILITY
摘要 <P>PROBLEM TO BE SOLVED: To identify a protein involved in a molecular mechanism between Akt and cell motility as well as to elucidate its function and find its application, relating to an application of Actin-Binding Protein, especially, relates to an application of Actin-Binding Protein Girdin (Akt Phosphorylation Enhancer), a new substrate of serine/threonine kinase, to disease associated with the protein. <P>SOLUTION: A protein or partial peptide thereof containing an amino acid sequence identical or substantially identical to a specific amino acid sequence is utilized in the screening of a compound or a salt thereof that activates or inhibits any of cell motility, cell migration and angiogenesis. <P>COPYRIGHT: (C)2013,JPO&INPIT
申请公布号 JP2013031443(A) 申请公布日期 2013.02.14
申请号 JP20120176352 申请日期 2012.08.08
申请人 NAGOYA UNIV 发明人 TAKAHASHI MASAHIDE;ENOMOTO ATSUSHI;MUROHARA TOYOAKI
分类号 C12Q1/02;A01K67/027;A61K31/7105;A61K31/711;A61K45/00;A61K48/00;A61P9/10;A61P25/00;A61P25/02;A61P35/00;C07K16/18;C12N5/10;C12N15/09;C12Q1/48;G01N33/15;G01N33/50;G01N33/566 主分类号 C12Q1/02
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