摘要 |
<P>PROBLEM TO BE SOLVED: To provide a prophylactic and/or therapeutic agent for diseases associated with autoimmunity, immune deficiency diseases or neurodegenerative diseases, in particular a prophylactic and/or therapeutic agent for sepsis. <P>SOLUTION: The prophylactic and/or therapeutic agent includes a compound of formula (I) or a salt thereof. In the formula (I), A<SP POS="POST">1</SP>is formula (A) or (B); A<SP POS="POST">2</SP>is the formula (B) or the like when A<SP POS="POST">1</SP>is the formula (A); Q<SP POS="POST">1</SP>is -NR<SP POS="POST">1</SP>R<SP POS="POST">2</SP>or the like; R<SP POS="POST">1</SP>and R<SP POS="POST">2</SP>are each a hydrogen atom, 1-10C alkyl or the like; Alk<SP POS="POST">3</SP>is a single bond or the like; X is a single bond or the like; R<SP POS="POST">3</SP>is 1-10C alkyl or the like; Q<SP POS="POST">2</SP>is -NR<SP POS="POST">4</SP>R<SP POS="POST">5</SP>or the like; R<SP POS="POST">4</SP>and R<SP POS="POST">5</SP>are each a hydrogen atom, 1-10C alkyl or the like; Alk<SP POS="POST">4</SP>is a single bond or the like; Ar is allylene or the like; Y is a single bond, -O- or the like; Z is a single bond, -N(R<SP POS="POST">10</SP>)- or the like; Alk<SP POS="POST">1</SP>and Alk<SP POS="POST">2</SP>are each methylene or the like; n<SP POS="POST">1</SP>and n<SP POS="POST">2</SP>are each an integer of 1-3; and R<SP POS="POST">10</SP>is a hydrogen atom, 1-10C alkyl or the like. <P>COPYRIGHT: (C)2013,JPO&INPIT |