发明名称 COMPOSITION COMPRISING A TLR AGONIST AND AN ANTIBODY SPECIFIC FOR AN ANTIGEN AND USES THEREOF AS VACCINE
摘要 The invention provides a TLR agonist and an antibody which binds to an antigen such as a ß-amyloid antigen for use in stimulating an immune response to the antigen in an individual. The TLR agonist can be delivered at the same time as the antibody, less than 48 hours before the antibody or after the antibody. The compositions and methods provided are useful for prevention or treatment of Alzheimer's disease.
申请公布号 WO2013020724(A1) 申请公布日期 2013.02.14
申请号 WO2012EP57963 申请日期 2012.05.01
申请人 GLAXOSMITHKLINE BIOLOGICALS S.A.;LAROCQUE, DANIEL;PALMANTIER, REMI;TRIBOUT-JOVER, PASCALE 发明人 LAROCQUE, DANIEL;PALMANTIER, REMI;TRIBOUT-JOVER, PASCALE
分类号 A61K39/395;A61K39/00;A61P25/28 主分类号 A61K39/395
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