Antimicrobial compounds of 1,4-naphtoquinone structure

摘要

The present invention relates to a compound having formula (I) wherein: R1 is chosen from the group consisting of: phenyl group, possibly substituted, -CH2-C6H4-R'1 group, R'1 being chosen from the group consisting of: H, -OH, halogen, alkyl, aryl, CHO, -CN, -NO2, -SRalpha, -ORalpha, -NRalphaRbeta, -CONRalphaRbeta, -COORalpha, and -NHCORalpha, Ralpha and Rbeta representing independently from each other H, an alkyl group or an aryl group, R'1 being preferably in para position, and -CH2-CO-R' group, R' representing an aryl or heteroaryl group, said aryl and heteroaryl groups being possibly substituted, R2 is chosen from the group consisting of: -OH and halogen, and R3, R4, R5 and R6 are in particular H, for its use for the prevention and/or the treatment of bacterial infections.