发明名称 |
COMPOSITIONS AND METHODS FOR PROVIDING HEMATOPOIETIC FUNCTION |
摘要 |
<p>The present invention relates to methods and compositions for providing hematopoietic function to human patients in need thereof, by selecting a pool of expanded human cord blood stem/progenitor cell samples for administration to the patient, wherein the samples in the pool collectively do not mismatch the patient at more than 2 of the HLA antigens or alleles typed in the patient; and administering the selected pool of expanded human cord blood stem/progenitor cell samples to the patient. Methods for obtaining the pools of expanded human cord blood stem/pro-genitor cell samples, banks of frozen pools of expanded human umbilical cord blood stem/progenitor cell samples, and methods for producing such banks are also provided herein.</p> |
申请公布号 |
EP2555781(A1) |
申请公布日期 |
2013.02.13 |
申请号 |
EP20110717077 |
申请日期 |
2011.04.11 |
申请人 |
FRED HUTCHINSON CANCER RESEARCH CENTER |
发明人 |
BERNSTEIN, IRWIN, D.;DELANEY, COLLEEN |
分类号 |
A61K35/14;A61K35/44;A61K35/50;A61P7/00;A61P35/02;C07K16/28;C12N5/0797 |
主分类号 |
A61K35/14 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|