发明名称 |
POLYOL MODIFIED AMINOGLYCOSIDE-LIPID CONJUGATES |
摘要 |
<p>In some aspects, the present invention provides aminoglycoside derivatives thereof that exhibit antibacterial activity. In some aspects, the aminoglycoside derivatives comprise compounds consisting of (a) an ammoglycoside group and (b) at least one hydrophobic carbamate and alkoxy group to the primary or secondary hydroxy position of the aminolvcoside group and salts thereof. Additionally, methods of treating and preventing bacterial infections using the aminoglycoside derivatives are also provided.</p> |
申请公布号 |
EP2556079(A2) |
申请公布日期 |
2013.02.13 |
申请号 |
EP20110765147 |
申请日期 |
2011.04.05 |
申请人 |
UNIVERSITY OF MANITOBA |
发明人 |
SCHWEIZER, FRANK;SMRITILEKHA, BERA;ZHANEL, GEORGE |
分类号 |
C07H15/00;A61K31/7036;A61P31/04;C07H13/02;C07H13/12;C07H15/04;C07H15/12;C07H15/18 |
主分类号 |
C07H15/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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