| 发明名称 |
PROCESS FOR THE PREPARATION OF MEMANTINE HYDROCHLORIDE |
| 摘要 |
<p>The present invention provides an improved process for the preparation of 1-bromo-3,5-dimethyladamantane. The present invention also provides a process for preparing free flowing solid of 1-acetamido-3,5-dimethyladamantane. The present invention further provides a process for the preparation of memantine hydrochloride substantially free of 1-amino-3,5,7-trimethyladamantane hydrochloride and/or 1-amino-3-methyladamantane hydrochloride impurity.</p> |
| 申请公布号 |
EP2555616(A1) |
申请公布日期 |
2013.02.13 |
| 申请号 |
EP20100849334 |
申请日期 |
2010.04.08 |
| 申请人 |
HETERO RESEARCH FOUNDATION |
发明人 |
PARTHASARADHI REDDY, BANDI;RATHNAKAR REDDY, KURA;MURALIDHARA REDDY, DASARI;RAJI REDDY, RAPOLU;RAMAKRISHNA REDDY, MATTA;VAMSI KRISHNA, BANDI |
| 分类号 |
A01N33/02;A61K31/13;C07C17/06;C07C209/62;C07C209/84;C07C231/10;C07C231/22 |
主分类号 |
A01N33/02 |
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