摘要 |
<p>An inactivated salmonid alphavirus, for use as a vaccine for preventing or reducing the incidence of fish pancreatic disease, comprises at least 3.75x108 TCID50/dose inactivated salmonid alphavirus (as determined by titration on CHH cells) and is compatible with other vaccine components from other viral, bacterial or fungal fish pathogens. The inactivated salmonid alphavirus is preferably derived from the SAV3 subtype. The invention further provides isolated salmonid alphavirus strains, and viruses with related nucleic acid sequence or phenotypic characteristics.</p> |