发明名称 |
Salts of methyl 2-((R)-(3-chlorophenyl)((R)-1-((S)-2-(methylamino)-3-((R)-tetrahydro-2H-pyran-3-yl)propylcarbamoyl)piperidin-3-yl)methoxy)ethylcarbamate |
摘要 |
Mucic acid salts of a compound represented by the following structural formula: are disclosed. In particular, single crystalline mucic acid salts of the compound represented by structural formula (I) are characterized by a variety of properties and physical measurements. Methods of producing the mucic acid salts, using the salts to antagonize one or more aspartic proteases, and methods of treating a number of aspartic protease mediated disorders using the salts are described herein.
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申请公布号 |
US8372978(B2) |
申请公布日期 |
2013.02.12 |
申请号 |
US20100851267 |
申请日期 |
2010.08.05 |
申请人 |
VITAE PHARMACEUTICALS, INC.;CLAREMON DAVID A.;SIMPSON ROBERT D.;JIA LANQI |
发明人 |
CLAREMON DAVID A.;SIMPSON ROBERT D.;JIA LANQI |
分类号 |
A61K31/453;A61P9/00;C07D413/12 |
主分类号 |
A61K31/453 |
代理机构 |
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主权项 |
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地址 |
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