发明名称 Recombiant lentivirus comprising an E2 alphavirus glycoprotein that binds to DC-SIGN
摘要 Methods and compositions are provided for delivery of a polynucleotide encoding a gene of interest, typically an antigen, to a dendritic cell (DC). The virus envelope comprises a DC-SIGN specific targeting molecule. The methods and related compositions can be used to treat patients suffering from a wide range of conditions, including infection, such as HIV/AIDS, and various types of cancers.
申请公布号 US8372390(B2) 申请公布日期 2013.02.12
申请号 US20100688779 申请日期 2010.01.15
申请人 CALIFORNIA INSTITUTE OF TECHNOLOGY;WANG PIN;YANG LILI;BALTIMORE DAVID 发明人 WANG PIN;YANG LILI;BALTIMORE DAVID
分类号 A01N63/00;A61K48/00 主分类号 A01N63/00
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