发明名称 |
COMPOSITIONS AND METHODS FOR THE TREATMENT AND PREVENTION OF FIBROTIC, INFLAMMATORY AND NEOVASCULARIZATION CONDITIONS |
摘要 |
<p>The present invention relates to compositions and methods for the treatment of diseases and conditions, including ocular diseases and conditions, characterized by aberrant fibrogenesis or scarring, inflammation and/or aberrant neovascularization or angiogenesis. The compositions and methods of the invention utilize immune-derived moieties that are specifically reactive against bioactive lipids and which are capable of decreasing the effective concentration of the bioactive lipids. In some embodiments, the immune-derived moiety is a monoclonal antibody that is reactive against sphinxine-1-phosphate (S1P) or lysophosphophatidic acid (LPA).</p> |
申请公布号 |
PT1948234(E) |
申请公布日期 |
2013.02.11 |
申请号 |
PT20060844226T |
申请日期 |
2006.10.27 |
申请人 |
LPATH, INC. |
发明人 |
ROGER A. SABBADINI;WILLIAM A. GARLAND;GLENN L STOLLER |
分类号 |
A61K39/395;C07K16/00;C12P21/08 |
主分类号 |
A61K39/395 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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