发明名称 SOLID DISPERSION FORMULATIONS AND METHODS OF USE THEREOF
摘要 The present invention relates to formulations and methods for increasing the bioavailability of 1-(4-benzhydrylpiperazin-1-yl)-3,3-diphenylpropan-1-one, 1-(3,3-diphenylpropanoyl)piperazine, or a salt thereof. In particular, the formulation can include one or more pharmaceutically acceptable matrix polymers to form a solid dispersion, e.g., a spray dried dispersion or a hot melt extrusion.
申请公布号 US2013035345(A1) 申请公布日期 2013.02.07
申请号 US201213414369 申请日期 2012.03.07
申请人 ZALICUS PHARMACEUTICALS LTD.;PADVAL MAHESH V.;GAUTSCHI JEFF T.;SMITHEY DANIEL T.;CREW MARSHALL D.;HARIANAWALA ABIZER 发明人 PADVAL MAHESH V.;GAUTSCHI JEFF T.;SMITHEY DANIEL T.;CREW MARSHALL D.;HARIANAWALA ABIZER
分类号 A61K31/495;A61P9/10;A61P25/00;A61P25/06;A61P25/08;A61P25/14;A61P25/16;A61P25/18;A61P27/16;A61P29/00;B29B9/00;B29C47/88;C12N5/07 主分类号 A61K31/495
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