发明名称 |
AMIDE DERIVATIVE AND DRUG CONTAINING SAME |
摘要 |
<p>[Problem] To provide a novel amide derivative having greater safety and having superior phosphodiesterase 4 inhibition. [Solution] The novel amide derivative, which is represented by general formula (1), has strong PDE 4 inhibiting activity, and is rapidly metabolized in the body, thus having an activity that attenuates, and so it is possible to suppress systemic adverse effects from arising. From said characteristics, the compound of the present invention is particularly suited to localized administration. In formula (1), A represents a condensed aromatic heterocyclic group represented by formula (a) or formula (b).</p> |
申请公布号 |
WO2013018372(A1) |
申请公布日期 |
2013.02.07 |
申请号 |
WO2012JP04934 |
申请日期 |
2012.08.02 |
申请人 |
KYORIN PHARMACEUTICAL CO., LTD.;KOHNO, YASUSHI;OCHIAI, KOJI;HIGUCHI, MORIO |
发明人 |
KOHNO, YASUSHI;OCHIAI, KOJI;HIGUCHI, MORIO |
分类号 |
C07D471/04;A61K31/444;A61P11/00;A61P11/02;A61P11/06;A61P17/00;A61P17/06;A61P25/00;A61P25/16;A61P25/28;A61P29/00 |
主分类号 |
C07D471/04 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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