发明名称 AMIDE DERIVATIVE AND DRUG CONTAINING SAME
摘要 <p>[Problem] To provide a novel amide derivative having greater safety and having superior phosphodiesterase 4 inhibition. [Solution] The novel amide derivative, which is represented by general formula (1), has strong PDE 4 inhibiting activity, and is rapidly metabolized in the body, thus having an activity that attenuates, and so it is possible to suppress systemic adverse effects from arising. From said characteristics, the compound of the present invention is particularly suited to localized administration. In formula (1), A represents a condensed aromatic heterocyclic group represented by formula (a) or formula (b).</p>
申请公布号 WO2013018372(A1) 申请公布日期 2013.02.07
申请号 WO2012JP04934 申请日期 2012.08.02
申请人 KYORIN PHARMACEUTICAL CO., LTD.;KOHNO, YASUSHI;OCHIAI, KOJI;HIGUCHI, MORIO 发明人 KOHNO, YASUSHI;OCHIAI, KOJI;HIGUCHI, MORIO
分类号 C07D471/04;A61K31/444;A61P11/00;A61P11/02;A61P11/06;A61P17/00;A61P17/06;A61P25/00;A61P25/16;A61P25/28;A61P29/00 主分类号 C07D471/04
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