摘要 |
<P>PROBLEM TO BE SOLVED: To provide a method of producing a germinal difluoro compound, by which a raw material substrate is easily available, operations are easy and a high yield is obtained. <P>SOLUTION: The method of producing the geminal difluoro compound includes a step of reacting fluorine-containing sulfuric acid enol esters with a fluorinating agent (hydrogen fluoride, "a salt or a complex comprising an organic base and hydrogen fluoride" or the like). The method is extremely useful for the production of the geminal difluoro compound, which solves all the problems in the prior arts. <P>COPYRIGHT: (C)2013,JPO&INPIT |