TREATMENT OF FIBROSIS USING MICRORNA-19B

摘要

The present invention provides a method for treating or preventing fibrosis comprising administering to a patient in need of such treatment or prevention an amount of microRNA-19b effective to treat or prevent said fibrosis. In some embodiments, the invention relates to inhibiting the activation of collagen-producing cells and thereby treating or preventing fibrosis. The methods of the invention also include detection of biomarkers that can be used to diagnose disease and/or evaluate the prognosis of a patient suffering from fibrosis or at risk of developing fibrosis, such as hepatic fibrosis. Such methods may be used to characterize the progression of diseases associated with fibrosis.