发明名称 |
Biosensor Electrode Mediators for Regeneration of Cofactors |
摘要 |
The present invention is based on the discovery of NAD+ and NADP+ mediator compounds that do not bind irreversibly to thiol groups in the active sites of intracellular dehydrogenase enzymes. Such mediator compounds avoid a common mode of enzyme inhibition. The mediators can therefore increase the stability and reliability of the electrical response in amperometric electrodes constructed from NAD- or NADP-dependent enzymes.
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申请公布号 |
US2013031780(A1) |
申请公布日期 |
2013.02.07 |
申请号 |
US201213561933 |
申请日期 |
2012.07.30 |
申请人 |
ABBOTT LABORATORIES;FORROW NIGEL J.;SANGHERA GURDIAL S.;WATKIN JARED L.;WALTERS STEPHEN |
发明人 |
FORROW NIGEL J.;SANGHERA GURDIAL S.;WATKIN JARED L.;WALTERS STEPHEN |
分类号 |
H05K3/10;C12Q1/00 |
主分类号 |
H05K3/10 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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