发明名称 |
PHARMACEUTICAL COMPOSITION COMPRISING FACTOR VII ENCAPSULATED IN MICELLES |
摘要 |
<p>The invention relates to a pharmaceutical composition comprising factor VII encapsulated in micelles formed from block copolymer molecules containing (i) a hydrophilic polymer segment consisting of a polyalkylene glycol and (ii) a hydrophobic polymer segment consisting of a polyamino acid, with said polyamino acid comprising exclusively amino acid residues selected from the goup consisting of histidine, lysine, aspartic acid and glutamic acid residues, wherein a part of said amino acid residues is substituted with a hydrophobic group.</p> |
申请公布号 |
WO2013018035(A1) |
申请公布日期 |
2013.02.07 |
申请号 |
WO2012IB53914 |
申请日期 |
2012.07.31 |
申请人 |
LFB BIOTECHNOLOGIES;NANOCARRIER CO., LTD;ARVIS, FLORENCE;HUILLE, SYLVAIN;HARADA, MITSUNORI |
发明人 |
ARVIS, FLORENCE;HUILLE, SYLVAIN;HARADA, MITSUNORI |
分类号 |
A61K9/107;A61K9/00;A61K38/36;A61K47/34;A61P7/04 |
主分类号 |
A61K9/107 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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