发明名称 PHARMACEUTICAL COMPOSITION FOR ORAL ADMINISTRATION
摘要 The present invention relates to a solid pharmaceutical composition for oral administration, containing the following components (A) and (B): 2-[4-[2-(benzimidazol-2-ylthio)ethyl]piperazin-1-yl]-N-[2,4-bis(methylthio)-6-methyl-3-pyridyl]acetamide (compound a) or an acid addition salt thereof, and (B) citric acid. An improvement is achieved in the dissolubility of the compound a, which is useful as a therapeutic agent for hypercholesterolemia, arteriosclerosis, and the like.
申请公布号 US2013035344(A1) 申请公布日期 2013.02.07
申请号 US201013519905 申请日期 2010.12.27
申请人 KOWA CO., LTD.;KOZAKI MASATO;SHIMOKAWA TATSUHARU;TANIZAWA YOSHIO 发明人 KOZAKI MASATO;SHIMOKAWA TATSUHARU;TANIZAWA YOSHIO
分类号 A61K31/496;A61P9/00;A61P9/10 主分类号 A61K31/496
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