发明名称 AMIDE DERIVATIVES BEARING A CYCLOPROPYLAMINOACARBONYL SUBSTITUENT USEFUL AS CYTOKINE INHIBITORS
摘要 The invention concerns a compound of the Formula (I), wherein Qa is heteroaryl and is substituted with halogeno; R1 and R2 are hydrogen; and Qb is phenyl or heteroaryl, and Qb may optionally bear 1 or 2 substituents selected from hydroxy, halogeno and (1-6C)alkyl, or a pharmaceutically-acceptable salt thereof; processes for their preparation, pharmaceutical compositions containing them and their use in the treatment of diseases or medical conditions mediated by cytokines.
申请公布号 US2013035346(A1) 申请公布日期 2013.02.07
申请号 US201213628958 申请日期 2012.09.27
申请人 ASTRAZENECA AB;ASTRAZENECA AB 发明人 BROWN DEARG SUTHERLAND;CUMMING JOHN GRAHAM;NASH IAN ALUN
分类号 A61K31/505;A61K31/16;A61K31/42;A61K31/426;A61K31/433;A61K31/437;A61K31/44;A61K31/506;A61P1/00;A61P9/00;A61P11/00;A61P11/06;A61P17/06;A61P19/02;A61P25/00;A61P29/00;A61P31/14;C07C237/28;C07D211/70;C07D213/30;C07D239/34;C07D261/06;C07D277/04;C07D277/24;C07D285/06;C07D285/10;C07D403/02;C07D417/02;C07D471/04 主分类号 A61K31/505
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