发明名称 |
MOLECULES AND METHODS FOR DEMETHYLATION OF METHYLATED NUCLEIC ACID SEQUENCES |
摘要 |
Demethylation of a methylated DNA sequence in a eukaryotic cell is described, utilising a molecule that includes at least a first domain that exhibits a cytidine deaminase activity and at least a second domain that confers either a specific or non-specific DNA binding activity. The molecules of the invention are useful in somatic cell nuclear transfer and also in cancer therapy
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申请公布号 |
US2013034881(A1) |
申请公布日期 |
2013.02.07 |
申请号 |
US201213646008 |
申请日期 |
2012.10.05 |
申请人 |
CELLCENTRIC LIMITED;CELLCENTRIC LIMITED |
发明人 |
REIK WOLF;MORGAN HUGH;CHAN CHUN-FUNG |
分类号 |
C12N9/00;C07H21/04;C12P19/34 |
主分类号 |
C12N9/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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