1,5-NAPHTHYRIDINE DERIVATIVE OR SALT THEREOF

摘要

A 1,5-naphthyridine derivative represented by general formula [1] (wherein each of R1, R2, R3, R4 and R5 represents a hydrogen atom, an -L-Z group (wherein Z represents a non-aromatic heterocyclic group or the like, and L represents a single bond or the like) or the like; R6 represents an -L-Z group or the like; each of R7 and R8 represents a hydrogen atom or the like; and Q represents an oxygen atom or the like) or a salt thereof has excellent inhibitory activity against the PI3K-AKT pathway and the Ras-Raf-MEK-ERK pathway, and is useful for the prophylaxis or treatment of diseases associated with the PI3K-AKT pathway and the Ras-Raf-MEK-ERK pathway.