发明名称 |
THERAPIES FOR TREATING HEPATITIS C VIRUS INFECTION |
摘要 |
A method of improving the pharmacokinetics of VX-222 in a patient infected with HCV comprises co-administering VX-222 and VX-950 to the patient. A method of treating a patient infected with HCV comprises administering VX-222 and VX-950 to the patient, wherein VX-222 is in an amount of about 20 mg to about 400 mg, and wherein VX-950 is in an amount of about 100 mg to about 1,500 mg. A method of treating a patient infected with HCV comprises administering a therapeutically effective amount of VX-222, wherein VX-222 is administered at an amount of about 20 mg to about 2,000 mg once a day.
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申请公布号 |
US2013034522(A1) |
申请公布日期 |
2013.02.07 |
申请号 |
US201213559995 |
申请日期 |
2012.07.27 |
申请人 |
VERTEX PHARMACEUTICALS INCORPORATED;ROSARIO MARIA;CHAURET NATHALIE;GEORGE SHELLEY;KIEFFER TARA LYNN;KOZIEL MARGARET JAMES;NICOLAS OLIVIER;PROULX LOUISE |
发明人 |
ROSARIO MARIA;CHAURET NATHALIE;GEORGE SHELLEY;KIEFFER TARA LYNN;KOZIEL MARGARET JAMES;NICOLAS OLIVIER;PROULX LOUISE |
分类号 |
A61K31/497;A61K31/7056;A61K38/21;A61P31/14 |
主分类号 |
A61K31/497 |
代理机构 |
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代理人 |
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地址 |
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