发明名称 MULTIPOTENTIAL EXPANDED MESENCHYMAL PRECURSOR CELL PROGENY (MEMP) AND USE THEREOF
摘要 <P>PROBLEM TO BE SOLVED: To provide multipotential expanded mesenchymal precursor progeny (MEMP's), characterized by the early developmental markers STRO-1<SP POS="POST">bri</SP>and ALP, methods for producing MEMP's and uses of MEMP's for therapeutic applications. <P>SOLUTION: The invention provides a composition containing MPC or progeny thereof, and stimulatory factors selected from the group consisting of 1&alpha;, 25-dihydroxyvitamin D3 (1, 25D), platelet-derived growth factor (PDGF), tumor necrosis factor &alpha; (TNF-&alpha;), interleukin-1&beta; (IL-1&beta;), and stroma-derived factor 1&alpha; (SDF-1&alpha;). <P>COPYRIGHT: (C)2013,JPO&INPIT
申请公布号 JP2013027394(A) 申请公布日期 2013.02.07
申请号 JP20120179934 申请日期 2012.08.14
申请人 MESOBLAST INC 发明人 GRONTHOS STAN;ZANNETTINO ANDREW CHRISTOPHER WILLIAM
分类号 C12N5/0775;A61K35/12;A61L27/00;A61P9/00;A61P9/10;A61P19/08;A61P19/10;A61P21/00;A61P25/00;C12N5/077;C12N5/10;C12N15/09 主分类号 C12N5/0775
代理机构 代理人
主权项
地址