发明名称 |
Tools for the identification of Lingo-1-, Lingo-2-, Lingo-3- and Lingo-4- ligands, and uses thereof |
摘要 |
The present invention relates to a system comprising coupling products formed by a monomer of a protein chosen from Lingo-1, Lingo-2, Lingo-3 and Lingo-4 and by a probe emitting a signal when said monomer undergoes conformational changes, and to a screening method using said system, enabling ligands of a protein chosen from Lingo-1, Lingo-2, Lingo-3 and Lingo-4 to be identified. The present invention is industrially applicable in the field of methods for detecting molecules, for detecting interaction between molecules and for molecular screening, and also in the medical field. |
申请公布号 |
EP2553453(A1) |
申请公布日期 |
2013.02.06 |
申请号 |
EP20110718448 |
申请日期 |
2011.04.01 |
申请人 |
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS |
发明人 |
MORISSET-LOPEZ, SEVERINE;BENEDETTI, HELENE |
分类号 |
G01N33/566;C07K14/705;C12N15/10;C12Q1/68;G01N33/542 |
主分类号 |
G01N33/566 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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