Mammal sestrins in the treatment of muscle wasting

摘要

The invention discloses a mammal sestrin product applicable in muscle atrophy, as well as any recombinant construction (vectors) comprising this mammal sestrin. A non-human animal model of muscle cell hypertrophy is also disclosed. In particular, the invention proposes tools for the treatment of atrophies of any aetiology, such as muscular dystrophies, cachexia, and atrophy related to malnutrition or to immobilization.