发明名称 |
Methods for determining dysregulation of methylation of brain expressed genes on the X chromosome to diagnose autism spectrum disorders |
摘要 |
The discovery that alterations in methylation, which can cause one or more genes on the single X chromosome in males to be partially silenced or overexpressed, constitute a predisposition to autism spectrum disorders is generally disclosed herein. These alterations provide the rationale and basis for methods to diagnose autism spectrum disorders.
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申请公布号 |
US8367417(B2) |
申请公布日期 |
2013.02.05 |
申请号 |
US201113170795 |
申请日期 |
2011.06.28 |
申请人 |
GREENWOOD GENETIC CENTER, INC.;STEVENSON ROGER E.;JONES JULIE R.;SKINNER CINDY D.;FRIEZ MICHAEL J. |
发明人 |
STEVENSON ROGER E.;JONES JULIE R.;SKINNER CINDY D.;FRIEZ MICHAEL J. |
分类号 |
C12Q1/68 |
主分类号 |
C12Q1/68 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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