发明名称 |
In vivo and ex vivo gene transfer into renal tissue using gutless adenovirus vectors |
摘要 |
A method for treating a renal disease in a subject is disclosed. The method includes administering into a kidney of the subject with an effective amount of a gutless adenoviral vector containing a polynucleotide encoding a therapeutic agent. The gutless adenoviral vector contains the nucleotide sequence of SEQ ID NO:13 or SEQ ID NO:15 and expresses the therapeutic agent in a kidney tissue of the subject.
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申请公布号 |
US8367056(B2) |
申请公布日期 |
2013.02.05 |
申请号 |
US201113023314 |
申请日期 |
2011.02.08 |
申请人 |
BIOVEC, LLC;SEHGAL LAKSHMAN R.;WONG JONATHAN |
发明人 |
SEHGAL LAKSHMAN R.;WONG JONATHAN |
分类号 |
A01N63/00;C07H21/04;C12N15/00 |
主分类号 |
A01N63/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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