发明名称 |
Methods, apparatus and systems for production, collection, handling, and imaging of tissue sections |
摘要 |
Methods, apparatus and systems for collecting thin tissue samples for imaging. Thin tissue sections may be cut from tissue samples using a microtome-quality knife. In one example, tissue samples are mounted to a substrate that is rotated such that thin tissue sections are acquired via lathing. Collection of thin tissue sections may be facilitated by a conveyor belt. Thin tissue sections may be mounted to a thin substrate (e.g., by adhering thin tissue sections to a thin substrate via a roller mechanism) that may be imaged, for example, by an electron beam (e.g., in an electron microscope). This tissue sections may be strengthened before cutting via a blockface thinfilm deposition technique and/or a blockface taping technique. An automated reel-to-reel imaging technique may be employed for collected/mounted tissue sections to facilitate random-access imaging of tissue sections and maintaining a comprehensive library including a large volume of samples.
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申请公布号 |
US8366857(B2) |
申请公布日期 |
2013.02.05 |
申请号 |
US20100695297 |
申请日期 |
2010.01.28 |
申请人 |
HAYWORTH KENNETH;HAYWORTH AMY AU |
发明人 |
HAYWORTH KENNETH;HAYWORTH AMY AU |
分类号 |
B32B37/22;B32B37/02;B32B38/04;B32B38/10;B65C9/04;B65C9/06;B65H75/00;B65H75/04;B65H81/02;G01N1/06 |
主分类号 |
B32B37/22 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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