发明名称 |
PHARMACEUTICAL FORMULATION IN THE FORM OF BILAYERED TABLETS COMPRISING HMG-COA REDUCTASE INHIBITOR AND IRBESARTAN |
摘要 |
Provided is a pharmaceutical formulation in the form of a bilayered tablet consisting of a first layer containing irbesartan or a pharmaceutically acceptable salt thereof and a second layer containing an HMG-CoA reductase inhibitor and a basic additive, which can improve the dissolution rate and stability of irbesartan and an HMG-CoA reductase inhibitor to enhance the bioavailability of the drug compared to conventional complex formulations and to minimize the generation of the related compounds, thereby being effectively used as a stable and superior therapeutic agent for hypertension and hypercholesterolemia.
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申请公布号 |
US2013028974(A1) |
申请公布日期 |
2013.01.31 |
申请号 |
US201113640590 |
申请日期 |
2011.05.13 |
申请人 |
HANMI SCIENCE CO., LTD;KIM YONG IL;NA YOUNG JUN;KIM MIN JUNG;KIM YOUNG-HUN;PARK JAE HYUN;WOO JONG SOO |
发明人 |
KIM YONG IL;NA YOUNG JUN;KIM MIN JUNG;KIM YOUNG-HUN;PARK JAE HYUN;WOO JONG SOO |
分类号 |
A61K31/4184;A61K9/20;A61P3/06 |
主分类号 |
A61K31/4184 |
代理机构 |
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代理人 |
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地址 |
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