HAIRPIN LOOP METHOD FOR DOUBLE STRAND POLYNUCLEOTIDE SEQUENCING USING TRANSMEMBRANE PORES
摘要
The invention relates to a new method of sequencing a double stranded target polynucleotide. The two strands of the double stranded target polynucleotide are linked by a bridging moiety. The two strands of the target polynucleotide are separated using a polynucleotide binding protein and the target polynucleotide is sequenced using a transmembrane pore.
申请公布号
WO2013014451(A1)
申请公布日期
2013.01.31
申请号
WO2012GB51786
申请日期
2012.07.25
申请人
OXFORD NANOPORE TECHNOLOGIES LIMITED;BROWN, CLIVE;CLARKE, JAMES;HALL, GRAHAM;HARPER, GAVIN;HERON, ANDREW;WHITE, JAMES
发明人
BROWN, CLIVE;CLARKE, JAMES;HALL, GRAHAM;HARPER, GAVIN;HERON, ANDREW;WHITE, JAMES