发明名称 |
REDUCTIVE ANIMATION PROCESS FOR PREPARATION OF DRONEDARONE USING ALDEHYDE INTERMEDIARY COMPOUND |
摘要 |
<p>The invention relates to a novel process for preparation of dronedarone of formula (I) and pharmaceutically acceptable salts thereof, characterized in that the compound of formula (II) is reacted with dibutylamine of formula (III), under reducing circumstances, and the obtained product is isolated and, if desired, converted into a pharmaceutically acceptable salt thereof, The invention also relates to some novel intermediary compounds and the preparation thereof.</p> |
申请公布号 |
WO2013014479(A1) |
申请公布日期 |
2013.01.31 |
申请号 |
WO2012HU00064 |
申请日期 |
2012.07.23 |
申请人 |
SANOFI;FRIESZ, ANTAL;DOMBRADY, ZSOLT |
发明人 |
FRIESZ, ANTAL;DOMBRADY, ZSOLT |
分类号 |
C07D307/80 |
主分类号 |
C07D307/80 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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