NOVEL 1,4-DIAZA-BICYCLO[3.2.2]NONYL OXADIAZOLYL DERIVATIVE AND ITS MEDICAL USE

摘要

THIS INVENTION RELATES TO A NOVEL 1,4-DIAZA-BICYCLO[3.2.2]NONYL OXADIAZOLYL DERIVATIVE AND ITS USE IN THE MANUFACTURE OF PHARMACEUTICAL COMPOSITIONS. THE COMPOUNDS OF THE INVENTION IS FOUND TO BE A CHOLINERGIC LIGAND AT THE NICOTINIC ACETYLCHOLINE RECEPTORS. DUE TO ITS PHARMACOLOGICAL PROFILE THE COMPOUNDS OF THE INVENTION MAY BE USEFUL FOR THE TREATMENT OF DISEASES OR DISORDERS AS DIVERSE AS THOSE RELATED TO THE CHOLINERGIC SYSTEM OF THE CENTRAL NERVOUS SYSTEM (CNS), THE PERIPHERAL NERVOUS SYSTEM (PNS), DISEASES OR DISORDERS RELATED TO SMOOTH MUSCLE CONTRACTION, ENDOCRINE DISEASES OR DISORDERS, DISEASES OR DISORDERS RELATED TO NEURO-DEGENERATION, DISEASES OR DISORDERS RELATED TO INFLAMMATION, PAIN, AND WITHDRAWAL SYMPTOMS CAUSED BY THE TERMINATION OF ABUSE OF CHEMICAL SUBSTANCES.