发明名称 |
OXAZOLE AND THIAZOLE DERIVATIVES AS SELECTIVE PROTEIN KINASE INHIBITORS (C-KIT) |
摘要 |
<p>The present invention relates to compounds of formula I or pharmaceutically acceptable salts thereof: wherein R1, R2, R3, A, Q, W and X are as defined in the description. These compounds selectively modulate, regulate, and/or inhibit signal transduction mediated by certain native and/or mutant proteine kinases implicated in a variety of human and animal diseases such as cell proliferative, metabolic, allergic, and degenerative disorders. More particularly, these compounds are potent and selective native and/or mutant c-kit inhibitors.</p> |
申请公布号 |
CA2840029(A1) |
申请公布日期 |
2013.01.31 |
申请号 |
CA20122840029 |
申请日期 |
2012.07.24 |
申请人 |
AB SCIENCE |
发明人 |
BENJAHAD, ABDELLAH;MOUSSY, ALAIN;CHEVENIER, EMMANUEL;PICOUL, WILLY;LERMET, ANNE;PEZ, DIDIER;MARTIN, JASON;SANDRINELLI, FRANCK |
分类号 |
C07D413/10;A61K31/422;A61K31/427;A61P35/00;C07D413/14;C07D417/10;C07D417/14 |
主分类号 |
C07D413/10 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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