发明名称 |
QUINOLINYL GLUCAGON RECEPTOR MODULATORS |
摘要 |
The present invention provides a compound of Formula I or a pharmaceutically acceptable salt thereof, wherein R1, R2, R3, A1, A2, A3, B1, B2, B3 and B4 are as defined herein. The compounds of Formula I have been found to act as glucagon antagonists or inverse agonists. Consequently, the compounds of Formula I and the pharmaceutical compositions thereof are useful for the treatment of diseases, disorders, or conditions mediated by glucagon. |
申请公布号 |
WO2013014569(A1) |
申请公布日期 |
2013.01.31 |
申请号 |
WO2012IB53575 |
申请日期 |
2012.07.12 |
申请人 |
PFIZER INC.;DIDIUK, MARY;FILIPSKI, KEVIN J.;GUZMAN-PEREZ, ANGEL;LEE, ESTHER C.;PFEFFERKORN, JEFFREY A.;STEVENS, BENJAMIN;TU, MEIHUA |
发明人 |
DIDIUK, MARY;FILIPSKI, KEVIN J.;GUZMAN-PEREZ, ANGEL;LEE, ESTHER C.;PFEFFERKORN, JEFFREY A.;STEVENS, BENJAMIN;TU, MEIHUA |
分类号 |
C07D215/38;A61K31/47;A61K31/502;A61P3/10;C07D239/94 |
主分类号 |
C07D215/38 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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