N[S(4-ARYL-TRIAZOL-3-YL)?-MERCAPTOACETYL]-P-AMINO BENZOIC ACIDS AS HIV REVERSE TRANSCRIPTASE INHIBITORS

摘要

A SERIES OF S-TRIAZOLYL ?-MERCAPTOACETANILIDES HAVING N-(?-MERCAPTOACETYL) P AMINO BENZOIC ACID DERIVATIVES. ARE PROVIDED, WHERE Q IS CO2H, OR A SALT OR ESTER THEREOF, OR A C(O)N-LINKED AMINO ACID. THE COMPOUNDS INHIBIT SEVERAL VARIANTS OF THE REVERSE TRANSCRIPTASE OF HIV, AND ARE USEFUL IN THE TREATMENT OF HIV INFECTIONS.