发明名称 |
HMG1 ANTIBODY FOR TREATING INFLAMMATORY CONDITIONS |
摘要 |
There is disclosed a pharmaceutical composition and method for treating sepsis, including septic shock and ARDS (acute respiratory distress syndrome), comprising administering an effective amount of a HMG1 antagonist. There is further disclosed a diagnostic method for monitoring the severity or potential lethality of sepsis or septic shock, comprising measuring the serum concentration of HMG1 in a patient exhibiting or at risk of exhibiting sepsis or septic shock symptoms. Lastly, there is disclosed a phamaceutical composition and method for effecting weight loss or treating obesity, comprising administering an effective amount of HMG1 or a therapeutically active HMG1 fragment.
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申请公布号 |
US2013028910(A1) |
申请公布日期 |
2013.01.31 |
申请号 |
US201213402057 |
申请日期 |
2012.02.22 |
申请人 |
THE FEINSTEIN INSTITUTE FOR MEDICAL RESEARCH;TRACEY KEVIN J.;WANG HAICHAO |
发明人 |
TRACEY KEVIN J.;WANG HAICHAO |
分类号 |
A61K39/395;G01N33/50;A61K31/70;A61K31/713;A61K38/00;A61K38/17;A61K45/00;A61K45/06;A61K48/00;A61P3/04;A61P29/00;A61P31/04;A61P43/00;C07H21/02;C07K16/18;G01N33/15;G01N33/566;G01N33/68 |
主分类号 |
A61K39/395 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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