发明名称 |
New strain of Salmonella enterica s. Typhimurium bacteria, its application, and method of obtaining the therapeutic vaccine vector |
摘要 |
The present invention relates to a new bacterial strain of Samonella enterica serovar Typhimurium VNP20009 deposited in the Polish Collection of Microorganisms under access no. B/00024 and its us in the production of a vaccine, especially an anti-cancer vaccine. The present invention also relates to a method of obtaining a therapeutic vaccine vector, characterized in that a genetic modification is introduced into the vector strain specific to cancer cells, resulting in the delayed over expression of a gene encoding a protein responsible for the invasive ability of this strain. |
申请公布号 |
PL213066(B1) |
申请公布日期 |
2013.01.31 |
申请号 |
PL20090387319 |
申请日期 |
2009.02.23 |
申请人 |
UNIWERSYTET JAGIELLONSKI W KRAKOWIE |
发明人 |
BERETA MICHAL |
分类号 |
C12N1/21;A61K35/74;A61K39/02;A61K39/112;A61P35/00;C12N15/03;C12N15/74;C12R1/42 |
主分类号 |
C12N1/21 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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