| 发明名称 |
ACTIVATION AND ACTIVATORS OF SIRT6 |
| 摘要 |
The invention provides a method of increasing a deacetylated activity of SIRT6 by contacting SIRT6 with an agent that binds SIRT6 and reduces the Km of SIRT6 for a substrate, thereby increasing the deacetylase activity of SIRT6. The invention also provides compounds of the formulas (II) and (III).
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| 申请公布号 |
US2013029930(A1) |
申请公布日期 |
2013.01.31 |
| 申请号 |
US201013516198 |
申请日期 |
2010.12.14 |
| 申请人 |
CORNELL UNIVERSITY;SAUVE ANTHONY;XU PING |
发明人 |
SAUVE ANTHONY;XU PING |
| 分类号 |
C07C309/51;A61K31/185;A61K31/706;C07C237/42;C12N9/96 |
主分类号 |
C07C309/51 |
| 代理机构 |
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代理人 |
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| 主权项 |
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| 地址 |
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