摘要 |
PURPOSE: A medium for activating cells is provided to improve survival ability and angiogenesis ability of the monocytes and to obtain a cell therapeutic agent for treating various diseases. CONSTITUTION: A medium for activating monocytes contains 100-1000 ng/ml of each of EGF(epidermal growth factor), TPO(thrombopoietin), Flt-3L, IGF(insulin-like growth factor)-1, GCP(granulocyte chemotactic protein)-2, and angiopoietin-1. The monocytes are human umbilical cord blood-derived monocytes, human peripheral blood monocytes, or human bone marrow-derived monocytes. The monocytes express one or more factors among VEGF-A, HGF, IGF-1, FGF-2, CTGF, PDGF-B, PIGF, and TGF-b. |