C-RING-SUBSTITUTED PREGN-4-ENE-21,17-CARBOLACTONES, AND PHARMACEUTICAL PREPARATIONS COMPRISING THE LATTER

摘要

The present invention relates to C-ring-substituted pregn-4-ene-21,17-carbolactones of the general formula Iin which Ris α- or &bgr;-methylene and Ris a hydrogen atom and Ris a bromine, chlorine or fluorine atom or Rand Rtogether are a bond. The novel compounds are gestagenic antimineralocorticoids.