| 摘要 |
PURPOSE: An external use skin composition for enhancing skin moisturization, elasticity, or anti-aging is provided to enhance gene expresison of hyaluronic acid synthase2(HAS2), to promote versican synthesis, and to enhance skin elasticity and skin moisturization. CONSTITUTION: An external use skin composition contains 0.0001-14 wt% of an Ulmus davidiana extract, a Dioscorea Japonica extract, or a Morus Alba leaf extract as an active ingredient. The composition promotes hyaluronic acid generation and enhances the expression of hyaluronic acid synthase gene, vesicant gene, and MMP-12 gene. The composition is used for enhancing moisturization, elasticity, anti-wrinkling, and anti-aging. [Reference numerals] (AA) HAS2 gene expression; (BB) Relative value(FOLD); (CC) Control group; (DD) Ulmus davidiana; (EE) Dioscorea Japonica; (FF) Morus Alba Leaf; (GG) Ulmus davidiana + Dioscorea Japonica; (HH) Ulmus davidiana + Morus Alba Leaf; (II) Dioscorea Japonica + Morus Alba Leaf; (JJ) Ulmus davidiana + Dioscorea Japonica + Morus Alba Leaf
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