发明名称 |
Anthracycline-Antibody Conjugates for Cancer Therapy |
摘要 |
The invention relates to therapeutic conjugates with the ability to target various antigens. The conjugates contain a targeting antibody or antigen binding fragment thereof and an anthracycline chemotherapeutic drug. The targeting antibody and the chemotherapeutic drug are linked via a linker comprising a hydrazide moiety.
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申请公布号 |
US8361464(B2) |
申请公布日期 |
2013.01.29 |
申请号 |
US20090564335 |
申请日期 |
2009.09.22 |
申请人 |
IMMUNOMEDICS, INC.;GRIFFITHS GARY L.;HANSEN HANS J.;QU ZHENGXING;GOLDENBERG DAVID M. |
发明人 |
GRIFFITHS GARY L.;HANSEN HANS J.;QU ZHENGXING;GOLDENBERG DAVID M. |
分类号 |
A61K39/395;A61K51/00 |
主分类号 |
A61K39/395 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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