发明名称 |
Cells in which activity of the protein involved in transportation of GDP-fucose is reduced or lost |
摘要 |
A cell in which the activity of a protein relating to transport of an intracellular sugar nucleotide, GDP-fucose, to the Golgi body is more decreased or deleted than its parent cell; a process for producing an antibody composition using the cell; a transgenic non-human animal or plant or the progenies thereof, in which genome is modified so as to have a decreased or deleted activity of a protein relating to transport of an intracellular sugar nucleotide, GDP-fucose, to the Golgi body; a process for producing an antibody composition from the animal or plant; and a medicament comprising the antibody composition.
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申请公布号 |
US8361751(B2) |
申请公布日期 |
2013.01.29 |
申请号 |
US20100782782 |
申请日期 |
2010.05.19 |
申请人 |
KYOWA HAKKO KIRIN CO., LTD;KANDA YUTAKA;SATOH MITSUO;MORI KATSUHIRO |
发明人 |
KANDA YUTAKA;SATOH MITSUO;MORI KATSUHIRO |
分类号 |
C12P21/08;A61P9/00;A61P29/00;A61P31/00;A61P35/00;A61P37/00;C07K14/47;C07K16/18;C07K16/28;C12N5/0781;C12N5/10;C12N15/82 |
主分类号 |
C12P21/08 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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