| 发明名称 |
TREATMENT OF BRAIN METASTASES WITH INHIBITORS OF ENDOTHELIN RECEPTORS IN COMBINATION WITH A CYTOTOXIC CHEMOTHERAPY AGENT. |
| 摘要 |
<p>The disclosure relates to an endothelin receptor antagonist for use in the prevention or treatment of brain metastases in combination with a cytotoxic chemotherapy agent, radiotherapy or both. The endothelin receptor antagonist may for example be bosentan, macitentan or a mixture of bosentan and macitentan.</p> |
| 申请公布号 |
MX2012001562(A) |
申请公布日期 |
2013.01.29 |
| 申请号 |
MX20120001562 |
申请日期 |
2010.08.09 |
| 申请人 |
BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM.* |
发明人 |
ISAIAH J. FIDLER;SUN-JIN KIM |
| 分类号 |
A01K67/00;A61K31/337;A61K31/4188;A61K31/506;A61P35/00;C12N5/00 |
主分类号 |
A01K67/00 |
| 代理机构 |
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代理人 |
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| 主权项 |
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| 地址 |
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