发明名称 |
Methods of forming microparticle coated medical device |
摘要 |
A drug-loaded microparticle is applied to a medical device for subsequent application to biological tissues. A method of formulating a drug-loaded microparticle and applying it to the surface of a medical device, such as a stent, is disclosed. The drug-loaded microparticle is formulated by combining a drug with various chemical solutions. Specified sizes of the microparticles and amounts of drug(s) contained within the microparticles may be varied by altering the proportions of the chemicals/solutions. In addition to various drugs, therapeutic substances and radioactive isotopes may also be loaded into the microparticles. The drug-loaded microparticle are suspended in a polymer solution forming a polymer matrix. The polymer matrix may be applied to the entire surface or only selected portions of the medical device via dipping, spraying or combinations thereof.
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申请公布号 |
US8361539(B2) |
申请公布日期 |
2013.01.29 |
申请号 |
US20030663181 |
申请日期 |
2003.09.15 |
申请人 |
ADVANCED CARDIOVASCULAR SYSTEMS, INC.;WU STEVEN Z.;HOSSAINY SYED F. A.;HARISH SAMEER;SANDERS-MILLARE DEBORRA;MIRZAEE DARYUSH |
发明人 |
WU STEVEN Z.;HOSSAINY SYED F. A.;HARISH SAMEER;SANDERS-MILLARE DEBORRA;MIRZAEE DARYUSH |
分类号 |
B05D3/00;A61K9/16;A61L31/10;A61L31/16 |
主分类号 |
B05D3/00 |
代理机构 |
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