发明名称 |
Detection and therapy of bacterial infection caused by Enterobacteriaceae |
摘要 |
The present invention provides a method for the treatment and/or prevention of bacterial infection caused by Enterobacteriaceae bacteria in central nervous system and/or peripheral blood circulation in a mammal by administering effective amount of outer membrane protein A (OmpA) or its derivatives to a mammal. Also provided are a method for vaccinating a mammal to produce an antibody against bacterial infection caused by Enterobacteriaceae family in central nervous system and/or peripheral blood circulation and a method of detecting or diagnosing bacterial infections caused by Enterobacteriaceae family in central nervous system and/or peripheral blood circulation in a mammal. An antibody and a kit on the basis of the vaccinating method and detecting/diagnosing method are also provided.
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申请公布号 |
US8361441(B2) |
申请公布日期 |
2013.01.29 |
申请号 |
US20090569363 |
申请日期 |
2009.09.29 |
申请人 |
TAIPEI MEDICAL UNIVERSITY;YANG YI-YUAN;WU HSUEH-HSIA;LEU SY-JYE;SHIH NENG-YAO;HUANG I-JEN;HSIEH WEN-SHYANG;LIU KO-JIUNN;HUANG SHIH-YI;SHIH YUNG-LUEN;LEE CHI-HSIN;HO YUAN-SOON;HSU SHIH-LAN |
发明人 |
YANG YI-YUAN;WU HSUEH-HSIA;LEU SY-JYE;SHIH NENG-YAO;HUANG I-JEN;HSIEH WEN-SHYANG;LIU KO-JIUNN;HUANG SHIH-YI;SHIH YUNG-LUEN;LEE CHI-HSIN;HO YUAN-SOON;HSU SHIH-LAN |
分类号 |
A61K49/00;A61K39/02;A61K39/112 |
主分类号 |
A61K49/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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