发明名称 Hydroxy-bisphosphonic acid derivatives as vector targeting bone tissue
摘要 The present invention relates to hydroxy-bisphosphonic acid derivatives corresponding to general formula (I): in which: -n and m denote, independently of one another, an integer ranging from 1 to 4, —X denotes an oxygen atom or an N—R3 group, —R1 and R3 denote, independently of one another, a linear or branched C1 to C6 alkyl group, and —R2 denotes a residue of a molecule of therapeutic or diagnostic interest, or pharmaceutically acceptable salts of said derivatives, and also the method for the preparation thereof and the therapeutic or diagnostic use thereof.
申请公布号 US8361993(B2) 申请公布日期 2013.01.29
申请号 US20090811602 申请日期 2009.01.05
申请人 UNIVERSITE DE NANTES;INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM);CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS);EGOROV MAXIM;FORTUN YANNICK;HEYMANN DOMINIQUE;LEBRETON JACQUES;MATHE MONIQUE;PADRINES MARC;REDINI FRANCOISE 发明人 EGOROV MAXIM;FORTUN YANNICK;HEYMANN DOMINIQUE;LEBRETON JACQUES;MATHE MONIQUE;PADRINES MARC;REDINI FRANCOISE
分类号 A01N57/00;A61K31/66;C07F9/02;C07F9/28 主分类号 A01N57/00
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