发明名称 |
Methods for detecting a Mycobacterium tuberculosis infection |
摘要 |
Methods for detecting an infection with Mycobacterium tuberculosis (Mtb) in a subject are disclosed. The methods include detecting the presence of CD8+ T cells that specifically recognize an Mtb polypeptide. The methods include in vitro assays for detecting the presence of CD8+ T cells in a biological sample, and in vivo assays that detect a delayed type hypersensitivity reaction. The methods can also include detecting Mtb polypeptides and polynucleotides. Reagents for the detection of an Mtb infection are also disclosed.
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申请公布号 |
US8361707(B2) |
申请公布日期 |
2013.01.29 |
申请号 |
US201113244126 |
申请日期 |
2011.09.23 |
申请人 |
OREGON HEALTH & SCIENCE UNIVERSITY;THE UNITED STATES OF AMERICA, DEPARTMENT OF VETERANS AFFAIRS;LEWINSOHN DAVID M.;LEWINSOHN DEBORAH A. |
发明人 |
LEWINSOHN DAVID M.;LEWINSOHN DEBORAH A. |
分类号 |
C12Q1/00;G01N33/53;G01N33/554;G01N33/567;G01N33/569 |
主分类号 |
C12Q1/00 |
代理机构 |
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代理人 |
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地址 |
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